Gene-Environment Interaction between the IL1RN Variants and Childhood Environmental Tobacco Smoke Exposure in Asthma Risk
نویسندگان
چکیده
منابع مشابه
Environmental tobacco smoke exposure and adult asthma.
the observed difference in total supplemental albuterol use of 0.24 puffs ( 1.90 vs. 1.66) is also surprisingly small. Finally, the statement that, to the authors’ knowledge, “no other wellcontrolled studies comparing salmeterol and montelukast have been published,” is difficult to understand, since two of the authors (A. E. and K. A. R.) are coauthors of a very similar study submitted 1.5 mont...
متن کاملPossible interaction between exposure to environmental tobacco smoke and therapy in children with asthma.
1. The aim of the study was to determine the carbachol and albuterol responsiveness in treated and untreated asthmatic and allergic children exposed to environmental tobacco smoke assessed by urinary cotinine measurements. 2. Forty-six asthmatic and allergic children with normal spirometric values were recruited. The doubling dose, concentration of carbachol producing a 2-fold increase in speci...
متن کاملEnvironmental tobacco smoke exposure and asthma in adults.
Environmental tobacco smoke (ETS) contaminates indoor air in homes and workplaces. Although the adverse effects of active cigarette smoking on the respiratory tract have been extensively characterized, the effects of ETS exposure on adult asthma have not yet been investigated extensively and the available data are limited. This article examines the evidence for ETS exposure as a cause of asthma...
متن کاملEnvironmental tobacco smoke, indoor allergens, and childhood asthma.
Both environmental tobacco smoke and indoor allergens can exacerbate already established childhood albeit primarily through quite disparate mechanisms. In infancy and childhood, environmental tobacco smoke (ETS) exposure is associated with measures of decreased flow in the airways, bronchial hyperresponsiveness, and increased respiratory infections, but the relationship between ETS and allergy ...
متن کاملEnvironmental tobacco smoke, parental atopy, and childhood asthma.
We hypothesized that the joint effect of genetic propensity to asthma and exposure to environmental tobacco smoke on the risk of childhood asthma is greater than expected on the basis of their independent effects. We performed a population-based 4-year cohort study of 2,531 children born in Oslo, Norway. We collected information on the child's health and environmental exposures at birth and whe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Environmental Research and Public Health
سال: 2020
ISSN: 1660-4601
DOI: 10.3390/ijerph17062036